Description

6-Chloro-3-Piperidin-4-Yl-1H-Indole is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for medicinal chemistry research and the development of novel therapeutic agents targeting the central nervous system. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for lead optimization and active pharmaceutical ingredient (API) synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead compound optimization due to its privileged indole-piperidine scaffold.
• Biochemical Tool Compound: Serves as a reference standard or probe in pharmacological assays to study specific receptor interactions.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects and scale-up activities.
• Academic Research: Utilized in university and institutional labs for exploratory organic synthesis and the development of new synthetic methodologies.

Basic Information

Product Name	6-Chloro-3-Piperidin-4-Yl-1H-Indole
CAS No.	180160-78-5
Molecular Formula	C13H15ClN2
Molecular Weight	234.73 g/mol
Synonyms	6-Chloro-3-(4-piperidinyl)-1H-indole; 3-(Piperidin-4-yl)-6-chloro-1H-indole; 6-Chloro-3-piperidin-4-ylindole; 1H-Indole, 6-chloro-3-(4-piperidinyl)-; 180160-78-5; 6-Chloro-3-(4-piperidyl)-1H-indole; 6-Chloro-3-(piperidin-4-yl)-1H-indole
EINECS	Contact for details

Quality Control

Our 6-Chloro-3-Piperidin-4-Yl-1H-Indole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.