Description

Mitratapide is a selective microsomal triglyceride transfer protein (MTP) inhibitor, a high-purity active pharmaceutical ingredient (API) critical for advanced pharmaceutical research and development. Its primary value lies in its targeted mechanism of action for investigating lipid metabolism disorders and related therapeutic pathways. This compound is essential for pharmaceutical companies, biotechnology research institutes, and academic laboratories focused on metabolic disease research, preclinical studies, and novel drug formulation.

Application

• Pharmaceutical API: Serves as the core active ingredient in the formulation of investigational new drugs targeting dyslipidemia.
• Metabolic Disease Research: A key tool compound for studying lipid absorption, chylomicron synthesis, and the role of MTP in metabolic pathways.
• Preclinical Development: Used in animal model studies to evaluate efficacy, pharmacokinetics, and safety profiles for potential lipid-lowering therapies.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Biochemical Assays: Utilized in in vitro screening assays to identify and characterize other compounds interacting with the MTP target.

Basic Information

Product Name	Mitratapide
CAS No.	179602-65-4
Molecular Formula	C33H35F3N4O4
Molecular Weight	608.66 g/mol
Synonyms	N-[(2S,3S)-1-(3-Chloro-5-fluorobenzyl)-3-(4-fluorophenyl)-4-oxo-2-azetidinyl]-2',6'-dimethoxy-4'-(trifluoromethyl)-[1,1'-biphenyl]-4-carboxamide; YM-53601; BMS-201038 (structural analog, related class); MTP Inhibitor; Microsomal Triglyceride Transfer Protein Inhibitor
EINECS	Contact for details

Quality Control

Our Mitratapide is manufactured under strict quality management systems to ensure it meets the stringent requirements for pharmaceutical research. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant ICH guidelines and can support development projects requiring material suitable for preclinical and clinical studies.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator after opening to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.