Description

4-Chloro-2'-Boric Acid Biphenyl is a high-purity, synthetically valuable organoboron compound, serving as a critical building block in advanced organic synthesis. Its core value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require reliable, high-quality intermediates for drug discovery, ligand synthesis, and the development of functional organic materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biphenyl or substituted biphenyl scaffolds.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific halogenated biaryl structures.
• Material Science: Serves as a monomer or building block for creating organic electronic materials, such as those used in OLEDs (Organic Light-Emitting Diodes) and semiconductors.
• Ligand & Catalyst Development: Employed in the preparation of novel phosphine or N-heterocyclic carbene (NHC) ligands for transition metal catalysis.
• Chemical Research: A fundamental reagent in academic and industrial R&D for exploring new C-C bond-forming methodologies and constructing molecular libraries.
• Fine Chemical Production: Integral to the multi-step synthesis of complex dyes, pigments, and other specialty fine chemicals.

Basic Information

Product Name	4-Chloro-2'-Boric Acid Biphenyl
CAS No.	179526-96-6
Molecular Formula	C12H10BClO2
Molecular Weight	232.47 g/mol
Synonyms	2'-(4-Chlorophenyl)phenylboronic acid; [1,1'-Biphenyl]-2-boronic acid, 4'-chloro-; 4'-Chloro[1,1'-biphenyl]-2-ylboronic acid; 4-Chloro-2'-biphenylboronic acid; (4'-Chloro[1,1'-biphenyl]-2-yl)boronic acid; 2-(4-Chlorophenyl)benzeneboronic acid; 4-Chloro-2-biphenylboronic Acid; 4-Chloro-2'-phenylboronic Acid Biphenyl
EINECS	Contact for details

Quality Control

Our 4-Chloro-2'-Boric Acid Biphenyl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for sensitive coupling reactions. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.