Description

Benzenemethanol, α-Ethynyl-4-Fluoro-, (Alphas)- (9Ci) is a specialized chiral fluorinated building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, combining a benzylic alcohol, an ethynyl group, and a fluorine substituent on the aromatic ring, which makes it a versatile precursor for constructing complex, bioactive molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries, where it serves as a critical intermediate for the development of new active ingredients, particularly in the areas of medicinal chemistry and crop protection.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), especially in fluorinated drug candidates.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the fluorine atom and chiral center can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of novel organic electronic materials and advanced polymers where fluorinated aromatic units are required.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting cutting-edge synthetic methodology and medicinal chemistry projects.

Basic Information

Item	Detail
Product Name	Benzenemethanol, α-Ethynyl-4-Fluoro-, (Alphas)- (9Ci)
CAS No.	179249-16-2
Molecular Formula	C9H7FO
Molecular Weight	150.15 g/mol
Synonyms	(αS)-α-Ethynyl-4-fluorobenzenemethanol; (S)-α-Ethynyl-4-fluorobenzyl alcohol; (S)-1-(4-Fluorophenyl)-2-propyn-1-ol; (S)-4-Fluoro-α-ethynylbenzyl alcohol; (S)-4-Fluoro-α-ethynylbenzenemethanol; (S)-1-(4-Fluorophenyl)prop-2-yn-1-ol; (αS)-4-Fluoro-α-ethynylbenzenemethanol; (S)-FPEA alcohol
EINECS	Contact for details

Quality Control

Our production of Benzenemethanol, α-Ethynyl-4-Fluoro-, (Alphas)- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high chemical purity suitable for research and development applications. All materials are characterized by modern analytical techniques including HPLC, GC, NMR, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity (assay), enantiomeric excess, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.