Description

3-Bromo-5-Fluoro-Benzenethiol is a high-purity, functionalized benzenethiol derivative characterized by its bromo and fluoro substituents, making it a versatile and valuable building block in advanced chemical synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors where precise structural modification is critical. It is needed by research chemists and process development scientists working on active pharmaceutical ingredients (APIs), liquid crystal materials, and specialized ligands for catalysis.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, leveraging the bioactivity imparted by the halogenated thiol group.
• Material Science: Acts as a monomer or functionalizing agent in the production of specialty polymers, liquid crystals, and organic electronic materials.
• Catalyst & Ligand Development: Employed to create novel sulfur-containing ligands for transition metal catalysis, enabling more efficient and selective chemical transformations.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new organic reactions and constructing complex heterocyclic compounds.
• Flavor & Fragrance Industry: Potential use as an intermediate for synthesizing specific sulfur-containing aroma chemicals, subject to purity and regulatory compliance.

Basic Information

Item	Detail
Product Name	3-Bromo-5-Fluoro-Benzenethiol
CAS No.	179161-18-3
Molecular Formula	C6H4BrFS
Molecular Weight	207.06 g/mol
Synonyms	3-Bromo-5-fluorobenzenethiol; 3-Bromo-5-fluorothiophenol; 5-Fluoro-3-bromobenzenethiol; 1-Bromo-3-fluoro-5-mercaptobenzene; (3-Bromo-5-fluorophenyl)thiol; Benzenethiol, 3-bromo-5-fluoro-; 3-Bromo-5-fluoro-1-thiophenol
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Fluoro-Benzenethiol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring traceability and consistency for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.