Description

Carbamic Acid, [4,5-Dihydro-4-(Iodomethyl)-2-Thiazolyl]-, 1,1-Dimethylethyl Ester (9Ci) CAS NO 179116-01-9 is a specialized iodomethyl-thiazoline carbamate derivative, serving as a high-value synthetic intermediate in advanced organic chemistry. Its core value lies in providing a protected, reactive scaffold for constructing complex heterocyclic molecules and pharmacologically active compounds. This product is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise building blocks for novel synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel thiazoline-containing drug candidates, particularly for central nervous system (CNS) and anti-infective therapies.
• Agrochemical Research: Used in developing new generation pesticides and herbicides, leveraging the thiazoline moiety for biological activity.
• Chemical Biology Probes: Serves as a precursor for activity-based probes (ABPs) targeting enzymes like proteases and hydrolases in mechanistic studies.
• Ligand & Catalyst Development: Employed in the preparation of chiral ligands and organocatalysts for asymmetric synthesis applications.
• Peptidomimetics: Integral for constructing constrained peptide analogs and macrocycles in medicinal chemistry programs.
• Material Science: Potential monomer or cross-linker in the development of functional polymers with specific degradation or recognition properties.

Basic Information

Item	Details
Product Name	Carbamic Acid, [4,5-Dihydro-4-(Iodomethyl)-2-Thiazolyl]-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	179116-01-9
Molecular Formula	C10H17IN2O2S
Molecular Weight	356.22 g/mol
Synonyms	tert-Butyl N-[4,5-dihydro-4-(iodomethyl)-1,3-thiazol-2-yl]carbamate; 2-[(tert-Butoxycarbonyl)amino]-4,5-dihydro-4-(iodomethyl)thiazole; 4,5-Dihydro-4-(iodomethyl)-2-thiazolamine, N-BOC-protected; BOC-4-(Iodomethyl)-4,5-dihydro-2-thiazolylamine; (4,5-Dihydro-4-iodomethyl-2-thiazolyl)carbamic Acid 1,1-Dimethylethyl Ester; 179116-01-9; BOC-AIT; N-Boc-4-(iodomethyl)-δ²-thiazoline
EINECS	Contact for details

Quality Control

Our production of Carbamic Acid, [4,5-Dihydro-4-(Iodomethyl)-2-Thiazolyl]-, 1,1-Dimethylethyl Ester adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity for research and development use. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. While not manufactured under current Good Manufacturing Practice (cGMP) unless specified, our quality system is designed to meet the exacting standards of pharmaceutical and agrochemical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light). Keep the container tightly sealed under an inert atmosphere if possible to maximize shelf-life stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.