Description

7-(Bromomethyl)-4-(4-Fluorophenyl)-2H-Chromen-2-One is a high-value synthetic intermediate characterized by its bromomethyl and fluorophenyl functional groups attached to a coumarin core. This compound is critical for researchers and manufacturers requiring precise molecular scaffolds for the development of novel active pharmaceutical ingredients (APIs) and advanced organic materials. It is primarily utilized in pharmaceutical R&D, agrochemical synthesis, and materials science for constructing complex heterocyclic systems.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly those targeting enzyme inhibition or receptor modulation.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or plant growth regulators leveraging the coumarin structure.
• Fluorescent Probe Synthesis: Serves as a precursor for creating coumarin-based fluorescent dyes and sensors used in bioimaging and analytical chemistry.
• Organic Light-Emitting Diode (OLED) Materials: Acts as a starting material for synthesizing electron-transport or emissive layer components in OLED devices.
• Polymer Chemistry: Can be incorporated as a functional monomer or cross-linking agent to impart specific properties to advanced polymers.
• Academic & Industrial R&D: A versatile reagent for methodological studies in organic synthesis, including cross-coupling and nucleophilic substitution reactions.

Basic Information

Product Name	7-(Bromomethyl)-4-(4-Fluorophenyl)-2H-Chromen-2-One
CAS No.	179113-49-6
Molecular Formula	C₁₆H₁₀BrFO₂
Molecular Weight	333.16 g/mol
Synonyms	4-(4-Fluorophenyl)-7-(bromomethyl)-2H-chromen-2-one; 7-Bromomethyl-4-(4-fluorophenyl)coumarin; 4-(4-Fluorophenyl)-7-(bromomethyl)coumarin; 2H-1-Benzopyran-2-one, 7-(bromomethyl)-4-(4-fluorophenyl)-; 179113-49-6; 4-(p-Fluorophenyl)-7-(bromomethyl)coumarin
EINECS	Contact for details

Quality Control

Our 7-(Bromomethyl)-4-(4-Fluorophenyl)-2H-Chromen-2-One is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing specific results for purity, identity, and impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.