Description

4,5,6,7-Tetrahydrothieno[3,2-C]Pyridin-2(3H)-One 4-Methylbenzenesulfonate is a high-purity pharmaceutical intermediate and organic building block of significant importance in modern synthetic chemistry. This compound is valued for its role as a key precursor in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting neurological and cardiovascular systems. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing novel therapeutic agents and advanced materials.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of clopidogrel and related thienopyridine-class antiplatelet agents.
• API Synthesis: Key precursor in the multi-step production of active pharmaceutical ingredients (APIs) for cardiovascular and cerebrovascular diseases.
• Chemical Research: Used in academic and industrial R&D for exploring new heterocyclic compounds and reaction pathways.
• Process Development: Serves as a reference standard and starting material for scaling up and optimizing manufacturing processes.
• Fine Chemical Production: Employed in the custom synthesis of specialized, high-value chemicals for various industrial applications.

Basic Information

Product Name	4,5,6,7-Tetrahydrothieno[3,2-C]Pyridin-2(3H)-One 4-Methylbenzenesulfonate
CAS No.	178688-49-8
Molecular Formula	C14H17NO3S2
Molecular Weight	311.42 g/mol
Synonyms	Clopidogrel Intermediate; 2-Oxo-4,5,6,7-tetrahydrothieno[3,2-c]pyridine p-toluenesulfonate; 2-Oxo-2,4,5,6,7,7a-hexahydrothieno[3,2-c]pyridin-5-ium 4-methylbenzenesulfonate; SR 25989; Methyl (2S)-2-(2-chlorophenyl)-2-((4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl)oxy)acetate p-toluenesulfonate salt precursor; Thieno[3,2-c]pyridin-2(3H)-one, 4,5,6,7-tetrahydro-, 4-methylbenzenesulfonate; 4-Methylbenzenesulfonic acid compound with 4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2(3H)-one (1:1)
EINECS	Contact for details

Quality Control

Our 4,5,6,7-Tetrahydrothieno[3,2-C]Pyridin-2(3H)-One 4-Methylbenzenesulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical intermediate applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability, consistency, and compliance with customer and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.