Description

4,5,6,7-Tetrahydrothieno[3,2-C]Pyridin-2(3H)-One is a heterocyclic organic compound featuring a fused thiophene and piperidine ring system, serving as a critical advanced pharmaceutical intermediate. This compound matters for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of novel therapeutic agents. Pharmaceutical R&D departments and fine chemical manufacturers need this high-purity intermediate to ensure the integrity and efficiency of their synthetic routes.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex drug molecules, particularly those targeting neurological and cardiovascular systems.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the multi-step manufacturing of proprietary APIs where the fused thiophene-piperidine scaffold is required.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the discovery of new chemical entities in drug discovery programs.
• Contract Manufacturing (CMO/CDMO): Supplied to contract development and manufacturing organizations for cGMP production of clinical trial materials and commercial drug substances.
• Chemical Reference Standard: Used as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.

Basic Information

Product Name	4,5,6,7-Tetrahydrothieno[3,2-C]Pyridin-2(3H)-One
CAS No.	178688-48-7
Molecular Formula	C7H9NOS
Molecular Weight	155.22 g/mol
Synonyms	2,3,4,5-Tetrahydrothieno[3,2-c]pyridin-6(7H)-one; 4,5,6,7-Tetrahydrothieno[3,2-c]pyridin-2-one; 6,7-Dihydro-4H-thieno[3,2-c]pyridin-5-one; Thieno[3,2-c]pyridin-2(3H)-one, 4,5,6,7-tetrahydro-; 2-Oxo-4,5,6,7-tetrahydrothieno[3,2-c]pyridine; Tetrahydrothienopyridinone
EINECS	Contact for details

Quality Control

Our 4,5,6,7-Tetrahydrothieno[3,2-C]Pyridin-2(3H)-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC for assay and impurity profiling, to meet the stringent requirements of pharmaceutical applications. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.