Description

Benzene, 1-Fluoro-4-Nitro-, Labeled With Carbon-14 (9Ci) is a high-specific-activity radiolabeled compound, an essential tool for advanced metabolic and pharmacokinetic studies. Its incorporation of the Carbon-14 isotope allows for precise tracking and quantification in complex biological and chemical systems, providing critical data for research and development. This product is primarily utilized by pharmaceutical, agrochemical, and environmental research organizations requiring definitive tracer analysis.

Application

• Tracer Studies in Drug Metabolism and Pharmacokinetics (DMPK): Used to elucidate the absorption, distribution, metabolism, and excretion (ADME) pathways of new chemical entities in preclinical research.
• Environmental Fate and Degradation Studies: Tracks the breakdown pathways and persistence of fluorinated nitroaromatic compounds in ecological systems.
• Mechanistic Organic Chemistry Research: Serves as a labeled substrate for studying reaction mechanisms, particularly nucleophilic aromatic substitution reactions involving fluoro- and nitro- substituents.
• Agrochemical Metabolism Research: Investigates the metabolic fate of pesticide intermediates or analogs in plants and soil.
• Radioligand Binding Assay Development: Can be used as a precursor for synthesizing high-specific-activity radioligands for receptor binding studies.
• Quality Control and Method Validation: Acts as an internal standard or reference material in advanced analytical techniques like LC-MS/MS for method development.

Basic Information

Product Name	Benzene, 1-Fluoro-4-Nitro-, Labeled With Carbon-14 (9Ci)
CAS No.	178603-76-4
Molecular Formula	C6H4FNO2 (¹⁴C labeled)
Molecular Weight	~141.10 g/mol (unlabeled)
Synonyms	4-Fluoronitrobenzene-¹⁴C; 1-Fluoro-4-nitrobenzene-¹⁴C; p-Fluoronitrobenzene-¹⁴C; 4-Nitrofluorobenzene-¹⁴C; [¹⁴C]-4-Fluoronitrobenzene; [¹⁴C]-p-Fluoronitrobenzene; ¹⁴C-Labeled 4-Fluoro-1-nitrobenzene; FNB-¹⁴C
EINECS	Contact for details

Quality Control

Every batch of this radiolabeled compound is produced and analyzed under strict quality control protocols to ensure high chemical, radiochemical, and isotopic purity. Analysis typically includes HPLC with UV and radiometric detection to confirm identity and purity. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing specific activity, radiochemical purity, chemical purity, and solvent composition. Our quality system is designed to meet the stringent requirements of GLP/GMP-compliant research environments.

Storage

Preserve in a tightly closed container, protected from light. Store at recommended temperatures (typically 2-8°C or as specified on the label) in a designated, secure area for radioactive materials. The product is strictly light-sensitive and must be protected from all light exposure during storage and handling to prevent decomposition.

Specification

Item	Specification
Appearance	Clear solution (color may vary)
Chemical Purity (HPLC)	≥ 98%
Radiochemical Purity (HPLC)	≥ 97%
Specific Activity	~9 Ci/mmol (Contact for exact value)
Solvent	Typically Toluene, Ethanol, or Acetonitrile
Concentration	Contact for details
Identification (IR/NMR)	Conforms to structure

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.