Description

Bicyclo[2.2.1]Heptan-1-Amine, 3,3-Dimethyl-2-Methylene-, (1R,4R)- (9Ci) is a high-purity, chiral amine building block characterized by its rigid bicyclic framework and exocyclic methylene group. This compound is valued for its role in asymmetric synthesis and as a precursor for advanced pharmaceutical intermediates and specialty ligands. It is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce sterically defined, functionalized amine moieties into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Asymmetric Catalyst Ligand Precursor: Used to synthesize novel chiral ligands for transition metal catalysis, enabling enantioselective transformations.
• Agrochemical Synthesis: Serves as a building block for creating bioactive molecules with herbicidal or insecticidal properties.
• Fine Chemical & Specialty Polymer Monomer: Incorporated into specialty polymers and advanced materials to impart rigidity and specific functionality.
• Academic & Industrial R&D: A valuable tool for methodological development in organic synthesis and medicinal chemistry research.
• Flavor & Fragrance Ingredient Synthesis: Used in the multi-step synthesis of complex odorants and flavor compounds.

Basic Information

Item	Details
Product Name	Bicyclo[2.2.1]Heptan-1-Amine, 3,3-Dimethyl-2-Methylene-, (1R,4R)- (9Ci)
CAS No.	178603-05-9
Molecular Formula	C10H17N
Molecular Weight	151.25 g/mol
Synonyms	(1R,4R)-3,3-Dimethyl-2-methylenenorbornan-1-amine; (1R,4R)-3,3-Dimethyl-2-methylenebicyclo[2.2.1]heptan-1-amine; endo-(1R,4R)-3,3-Dimethyl-2-methylenenorbornan-1-amine; 2-Methylene-3,3-dimethylbicyclo[2.2.1]heptan-1-amine, (1R,4R)-; Chiral Norbornane Amine Derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of Bicyclo[2.2.1]Heptan-1-Amine, 3,3-Dimethyl-2-Methylene-, (1R,4R)- (9Ci) is produced and tested under a strict quality management system. Our products undergo rigorous quality testing, including chiral purity analysis, to ensure compliance with exacting industry standards for research and process chemistry. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.