Description

Bicyclo[2.2.1]Heptan-1-Amine, 7,7-Dimethyl-2-Methylene-, (1S,4S)- (9Ci) is a high-purity, chiral amine building block characterized by its rigid bicyclic framework and exocyclic methylene group. This compound matters as a sophisticated intermediate for synthesizing complex molecules, offering precise stereochemical control in asymmetric synthesis. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its structural rigidity can enhance biological activity and environmental stability.
• Catalyst & Ligand Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric hydrogenation and carbon-carbon bond-forming reactions.
• Fine Chemical Production: Employed in the synthesis of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Material Science Research: Investigated as a monomer or cross-linking agent for creating polymers with unique thermal and mechanical properties.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic synthesis and for exploring new chemical spaces in discovery chemistry.

Basic Information

Product Name	Bicyclo[2.2.1]Heptan-1-Amine, 7,7-Dimethyl-2-Methylene-, (1S,4S)- (9Ci)
CAS No.	178448-80-1
Molecular Formula	C10H17N
Molecular Weight	151.25 g/mol
Synonyms	(1S,4S)-7,7-Dimethyl-2-methylenebicyclo[2.2.1]heptan-1-amine; (1S,4S)-1-Amino-7,7-dimethyl-2-methylenenorbornane; endo-1-Amino-7,7-dimethyl-2-methylenenorbornane; 2-Norbornanamine, 7,7-dimethyl-2-methylene-, (1S,4S)-; Chiral Norbornane Amine Derivative; Bicyclo[2.2.1]heptane-1-amine, 7,7-dimethyl-2-methylene-, (1S,4S)-; (1S,4S)-1-Amino-2-methylidene-7,7-dimethylnorbornane
EINECS	Contact for details

Quality Control

Our production of Bicyclo[2.2.1]Heptan-1-Amine, 7,7-Dimethyl-2-Methylene-, (1S,4S)- (9Ci) adheres to strict quality management protocols. Every batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC and GC, to ensure high chemical and enantiomeric purity suitable for sensitive synthetic applications. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (enantiomeric excess)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.