Description

1-(3-Bromopropyl)-4-(Trifluoromethyl)Benzene is a versatile bromoalkyl aromatic building block characterized by a reactive bromopropyl side chain and a stable, electron-withdrawing trifluoromethyl group. This molecular architecture makes it a critical intermediate for the synthesis of more complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical and life science industries for constructing novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those requiring a fluorinated aromatic moiety for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the trifluoromethyl group can improve lipophilicity and biological activity.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes.
• Cross-Coupling Reactions: The bromopropyl chain is amenable to various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) for carbon-carbon bond formation.
• Functional Polymer Modification: Incorporated into polymer backbones or as a pendant group to impart specific chemical and physical properties, such as altered solubility or refractive index.
• Ligand & Catalyst Development: Utilized in the preparation of specialized ligands for catalysis or as a scaffold for catalyst design in asymmetric synthesis.

Basic Information

Product Name	1-(3-Bromopropyl)-4-(Trifluoromethyl)Benzene
CAS No.	178369-93-2
Molecular Formula	C10H10BrF3
Molecular Weight	267.09 g/mol
Synonyms	4-(3-Bromopropyl)benzotrifluoride; 1-Bromo-3-[4-(trifluoromethyl)phenyl]propane; 3-(4-Trifluoromethylphenyl)propyl bromide; α,α,α-Trifluoro-4-(3-bromopropyl)toluene; 4-(3-Bromopropyl)α,α,α-trifluorotoluene; 3-(p-Trifluoromethylphenyl)propyl bromide; p-(3-Bromopropyl)benzotrifluoride
EINECS	Contact for details

Quality Control

Our production of 1-(3-Bromopropyl)-4-(Trifluoromethyl)Benzene adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and scale-up applications. Each lot is analyzed via GC, HPLC, and NMR to confirm identity and purity, with all critical impurities monitored and controlled. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials. The container should be kept tightly sealed to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.