Description

Bicyclo[2.2.1]Heptan-2-Ol, 5-Amino-, (1R,2S,4R,5S)-Rel- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. This compound matters because its rigid bicyclic framework and strategically positioned amino and hydroxyl functional groups make it a versatile precursor for constructing complex molecular architectures. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for applications such as asymmetric synthesis, medicinal chemistry, and the development of novel catalysts and ligands.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of active pharmaceutical ingredients (APIs), particularly in projects requiring rigid, three-dimensional scaffolds.
• Asymmetric Catalyst & Ligand Synthesis: Serves as a core structure for designing and synthesizing novel chiral ligands and organocatalysts used in enantioselective transformations.
• Medicinal Chemistry & Drug Discovery: Utilized in lead optimization and structure-activity relationship (SAR) studies to explore new chemical space and modulate the physicochemical properties of drug candidates.
• Agrochemical Research: Employed in the synthesis of novel, biologically active compounds for crop protection and pest management.
• Advanced Material Science: Potential building block for specialty polymers, dendrimers, or functional materials that benefit from its specific stereochemistry and functionality.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and stereochemistry at universities and corporate research laboratories.

Basic Information

Product Name	Bicyclo[2.2.1]Heptan-2-Ol, 5-Amino-, (1R,2S,4R,5S)-Rel- (9Ci)
CAS No.	178111-37-0
Molecular Formula	C7H13NO
Molecular Weight	127.18 g/mol
Synonyms	(1R,2S,4R,5S)-5-Aminobicyclo[2.2.1]heptan-2-ol; rel-(1R,2S,4R,5S)-5-Amino-2-norbornanol; 5-Amino-2-norbornanol (specific stereoisomer); 5-Aminonorbornan-2-ol; endo,endo-5-Amino-2-norbornanol; Bicyclo[2.2.1]heptan-2-ol, 5-amino-, (1R,2S,4R,5S)-rel-; Chiral 5-Amino-2-norbornanol; Amino alcohol building block CAS 178111-37-0.
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.1]Heptan-2-Ol, 5-Amino-, (1R,2S,4R,5S)-Rel- (9Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity analysis, to meet the exacting standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.