Description

2-Chlorothiophene-3-Boronic Acid is a versatile organoboron building block, specifically a boronic acid derivative of a halogenated thiophene. Its primary value lies in enabling efficient carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone of modern synthetic chemistry. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require the precise construction of complex heterocyclic molecules.

Application

• Pharmaceutical Intermediate: A key synthon for constructing active pharmaceutical ingredients (APIs), particularly those containing functionalized thiophene cores.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides with tailored biological activity.
• Material Science: Serves as a monomer or precursor in the synthesis of conjugated polymers and organic electronic materials for OLEDs and semiconductors.
• Ligand & Catalyst Development: Employed to create novel bidentate or polydentate ligands for transition metal catalysis.
• Chemical Research: A valuable reagent for medicinal chemistry and process R&D for exploring new chemical spaces and reaction pathways.
• Fine Chemical Production: Integral in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	2-Chlorothiophene-3-Boronic Acid
CAS No.	177734-82-6
Molecular Formula	C4H4BClO2S
Molecular Weight	162.40 g/mol
Synonyms	(2-Chloro-3-thienyl)boronic acid; 2-Chloro-3-thiopheneboronic acid; 2-Chlorothiophene-3-boronic acid pinacol ester (protected form); 3-Borono-2-chlorothiophene; 2-Chloro-3-boronothiophene; Boronic acid, B-(2-chloro-3-thienyl)-; 2-Chloro-thiophene-3-ylboronic acid
EINECS	Contact for details

Quality Control

Our 2-Chlorothiophene-3-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.