Description

2H-Isoindole-2-Carboxylicacid,3A-Amino-1,3,3A,7A-Tetrahydro-,Methylester is a high-purity, advanced pharmaceutical intermediate with a complex fused-ring structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and other therapeutic areas.
• Organic Synthesis Building Block: Used in complex multi-step organic syntheses to construct intricate molecular architectures due to its reactive amino and ester functional groups.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and combinatorial chemistry libraries to explore new bioactive molecules.
• Process Chemistry Development: Serves as a starting material or intermediate in scaling up synthetic routes from laboratory to pilot and commercial production.
• Fine Chemical Production: Utilized in the manufacture of specialty chemicals, catalysts, and ligands for asymmetric synthesis.

Basic Information

Product Name	2H-Isoindole-2-Carboxylicacid,3A-Amino-1,3,3A,7A-Tetrahydro-,Methylester
CAS No.	177565-40-1
Molecular Formula	C10H12N2O2
Molecular Weight	192.22 g/mol
Synonyms	3a-Amino-1,3,3a,7a-tetrahydro-2H-isoindole-2-carboxylic acid methyl ester; Methyl 3a-amino-1,3,3a,7a-tetrahydro-2H-isoindole-2-carboxylate; 3a-Amino-1,3,3a,7a-tetrahydroisoindole-2-carboxylic acid methyl ester; (3aR,7aS)-3a-Amino-1,3,3a,7a-tetrahydro-2H-isoindole-2-carboxylic acid methyl ester (enantiomer); 2H-Isoindole-2-carboxylic acid, 3a-amino-1,3,3a,7a-tetrahydro-, methyl ester; 177565-40-1; Amino-isoindole methyl ester derivative
EINECS	Contact for details

Quality Control

Our 2H-Isoindole-2-Carboxylicacid,3A-Amino-1,3,3A,7A-Tetrahydro-,Methylester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.