Description

1H-Indole-1,3-Dicarboxylic Acid, 1-(1,1-Dimethylethyl)3-Ethyl Ester is a high-purity, synthetically valuable indole derivative, serving as a critical protected intermediate in advanced organic synthesis. Its primary value lies in enabling the precise construction of complex molecular architectures, particularly in pharmaceutical research and development. This compound is essential for chemists and manufacturers in the life sciences sector who require reliable, high-quality building blocks for creating novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key protected building block in the multi-step synthesis of complex drug candidates, particularly those containing indole or tryptamine cores.
• Agrochemical Research: Used in the development of novel pesticides and herbicides where the indole scaffold imparts specific biological activity.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing heterocyclic compounds, facilitating reactions like cross-coupling, alkylation, and amidation.
• Material Science Precursor: Potential starting material for the synthesis of specialized organic ligands, dyes, or photoactive compounds.

Basic Information

Product Name	1H-Indole-1,3-Dicarboxylic Acid, 1-(1,1-Dimethylethyl)3-Ethyl Ester
CAS No.	177200-90-7
Molecular Formula	C₁₇H₂₁NO₄
Molecular Weight	303.35 g/mol
Synonyms	1-(tert-Butyl) 3-ethyl 1H-indole-1,3-dicarboxylate; tert-Butyl 3-(ethoxycarbonyl)-1H-indole-1-carboxylate; 1-tert-Butoxycarbonylindole-3-carboxylic Acid Ethyl Ester; 1-Boc-indole-3-carboxylic Acid Ethyl Ester; 1-Boc-3-ethoxycarbonylindole; Ethyl 1-Boc-indole-3-carboxylate; 1H-Indole-1,3-dicarboxylic acid, 1-(1,1-dimethylethyl) 3-ethyl ester; 1-Boc-3-COOEt-indole
EINECS	Contact for details

Quality Control

Our 1H-Indole-1,3-Dicarboxylic Acid, 1-(1,1-Dimethylethyl)3-Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research-standard materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0%
Related Substances (HPLC)	Total impurities ≤3.0%
Any single impurity	≤1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.