Description

Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid, 2-Methyl-, (1S-Endo)- (9Ci) is a high-purity, chiral bicyclic carboxylic acid derivative, serving as a critical advanced intermediate in sophisticated organic syntheses. Its unique sterically defined, endo-configured bicyclic framework makes it an invaluable building block for constructing complex molecular architectures with precise stereochemistry. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients, chiral ligands, and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the production of advanced, stereospecific pesticides and herbicides where the defined spatial orientation is crucial for biological activity.
• Chiral Ligand & Catalyst Precursor: Serves as a foundational structure for synthesizing proprietary chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials with specific structural and optical properties.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in organic chemistry, particularly in Diels-Alder and other cycloaddition reactions.
• Fine Chemical Production: Acts as a high-value intermediate in the custom synthesis of complex fragrance and flavor molecules.

Basic Information

Product Name	Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid, 2-Methyl-, (1S-Endo)- (9Ci)
CAS No.	176774-74-6
Molecular Formula	C9H12O2
Molecular Weight	152.19 g/mol
Synonyms	(1S-endo)-2-Methylbicyclo[2.2.1]hept-5-ene-2-carboxylic acid; (1S,2R,4R)-2-Methylbicyclo[2.2.1]hept-5-ene-2-carboxylic acid; endo-2-Methyl-5-norbornene-2-carboxylic acid; 2-Methyl-2-norbornene-5-carboxylic acid; 2-Methylbicyclo[2.2.1]hept-5-ene-2-carboxylic acid, endo-; 2-Methyl-5-norbornene-2-carboxylic acid, endo-; Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid, 2-methyl-, (1S-endo)-
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid, 2-Methyl-, (1S-Endo)- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.