Description

(R,R)-(-)-N,N'-Bis(3,5-Di-tert-Butylsalicylidene)-1,2-Cyclohexanediamino-Cobalt(II) is a highly specialized, chiral salen-type cobalt complex that serves as a sophisticated catalyst and ligand in asymmetric synthesis. Its value lies in its ability to impart precise stereochemical control in critical organic transformations, enabling the production of enantiomerically pure intermediates. This compound is essential for research and development in advanced pharmaceutical manufacturing and fine chemical synthesis, where high selectivity and yield are paramount.

Application

• Asymmetric Catalysis: A key catalyst for enantioselective epoxidation, cyclopropanation, and other C–H functionalization reactions.
• Pharmaceutical Intermediate Synthesis: Used in the production of chiral active pharmaceutical ingredients (APIs) and complex drug molecules.
• Polymerization Catalyst: Employed in the synthesis of stereoregular polymers and advanced polymeric materials.
• Organic Ligand in Coordination Chemistry: Serves as a precursor or model compound for developing new metal-organic frameworks (MOFs) and catalysts.
• Academic & Industrial R&D: A critical reagent for methodological development in organic and organometallic chemistry laboratories.
• Fine Chemical Production: Facilitates the synthesis of high-value, optically pure flavors, fragrances, and agrochemicals.

Basic Information

Product Name	(R,R)-(-)-N,N'-Bis(3,5-Di-tert-Butylsalicylidene)-1,2-Cyclohexanediamino-Cobalt(II)
CAS No.	176763-62-5
Molecular Formula	C44H58CoN2O2
Molecular Weight	705.87 g/mol
Synonyms	(R,R)-(-)-N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminocobalt(II); (R,R)-Salen Cobalt(II) Complex; Cobalt(II) (R,R)-(-)-N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediamine; (R,R)-Jacobsen's Cobalt Catalyst; (R,R)-Co(salen); Chiral Cobalt Salen Complex; (R,R)-(-)-1,2-Cyclohexanediamino-N,N'-bis(3,5-di-tert-butylsalicylidene)cobalt(II)
EINECS	Contact for details

Quality Control

Our production of (R,R)-(-)-N,N'-Bis(3,5-Di-tert-Butylsalicylidene)-1,2-Cyclohexanediamino-Cobalt(II) adheres to stringent quality protocols to ensure batch-to-batch consistency and high catalytic performance. Each lot is characterized using advanced analytical techniques, and a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and identity is provided. We support cGMP and ISO compliant manufacturing for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and easily oxidized; therefore, containers must be kept tightly sealed and handled in a dry environment to maintain stability and catalytic activity.

Specification

Item	Specification
Appearance	Dark brown to black crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC/Chiral Column)	≥ 99.0% e.e.
Loss on Drying	≤ 1.0 %
Residue on Ignition (Sulfated Ash)	≤ 0.5 %
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.