Description

2-(1-Methyl-1H-Indol-3-Yl)Propanenitrile (CAS NO 176688-64-5) is a versatile indole-based nitrile compound serving as a critical synthetic intermediate in advanced organic chemistry. Its molecular structure makes it a valuable building block for constructing complex heterocyclic frameworks, particularly in the development of active pharmaceutical ingredients (APIs). This high-purity intermediate is essential for research and production chemists in the pharmaceutical, agrochemical, and material science industries seeking to develop novel compounds with specific biological or functional properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its indole core for biological activity.
• Material Science Research: Serves as a monomer or functional unit in the development of specialty polymers and organic electronic materials.
• Chemical Biology Probes: Employed in the creation of fluorescent tags or molecular probes for studying biological systems.
• Academic & R&D: A fundamental reagent for methodological development in organic synthesis and heterocyclic chemistry within university and industrial research labs.

Basic Information

Product Name	2-(1-Methyl-1H-Indol-3-Yl)Propanenitrile
CAS No.	176688-64-5
Molecular Formula	C₁₂H₁₂N₂
Molecular Weight	184.24 g/mol
Synonyms	3-(2-Cyanoethyl)-1-methylindole; 1-Methyl-3-(2-cyanoethyl)indole; 2-(1-Methylindol-3-yl)propanenitrile; 2-(1-Methyl-1H-indol-3-yl)propanenitrile; α-(1-Methyl-1H-indol-3-yl)propionitrile; 1-Methyl-3-(2-cyanoethyl)-1H-indole; (1-Methyl-1H-indol-3-yl)propanenitrile
EINECS	Contact for details

Quality Control

Our 2-(1-Methyl-1H-Indol-3-Yl)Propanenitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.