Description

4-T-Butoxyphenylboronic Acid is a high-purity organoboron compound, specifically a substituted phenylboronic acid, serving as a critical building block in modern synthetic chemistry. Its primary value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to develop active pharmaceutical ingredients (APIs), novel crop protection agents, and organic electronic materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific biaryl architectures.
• Material Science Research: Serves as a monomer or building block for creating organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs).
• Chemical Biology & Sensing: Utilized in the development of molecular probes, sensors, and diagnostic tools that leverage boronic acid-diol interactions.
• Academic & Process R&D: A valuable reagent for method development, catalysis studies, and exploring new synthetic pathways in academic and industrial laboratories.
• Fine Chemical Production: Employed in the custom synthesis of specialty chemicals, flavors, and fragrances requiring the introduction of a tert-butoxyphenyl moiety.

Basic Information

Item	Details
Product Name	4-T-Butoxyphenylboronic Acid
CAS No.	176672-49-4
Molecular Formula	C10H15BO3
Molecular Weight	194.04 g/mol
Synonyms	4-(tert-Butoxy)phenylboronic Acid; p-(tert-Butoxy)phenylboronic Acid; 4-tert-Butoxyphenylboronic Acid; (4-(tert-Butoxy)phenyl)boronic Acid; 4-Tert-Butoxyphenylboronic Acid; Boronic acid, B-[4-(1,1-dimethylethoxy)phenyl]-; 4-(tert-Butyloxy)phenylboronic Acid
EINECS	Contact for details

Quality Control

Our 4-T-Butoxyphenylboronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from incompatible materials such as strong oxidizers.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.