Description

3H-Pyrrolizin-3-One,Hexahydro-1-Methoxy-,(1S-Trans)-(9Ci) is a high-purity, stereochemically defined chiral compound, identified by CAS number 176242-19-6. This advanced pharmaceutical intermediate is critical for ensuring the efficacy and safety of final drug products, particularly in enantioselective synthesis. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of complex, biologically active molecules and novel drug candidates.
• Asymmetric Synthesis: Used as a precursor or reagent in enantioselective catalytic processes to introduce specific stereocenters.
• Medicinal Chemistry Research: Serves as a core scaffold or starting material for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry Development: Employed in scaling up synthetic routes for the commercial production of high-value fine chemicals and APIs.
• Academic & Industrial R&D: Utilized in chemical libraries and for exploring new synthetic methodologies involving pyrrolizidine-based structures.

Basic Information

Product Name	3H-Pyrrolizin-3-One,Hexahydro-1-Methoxy-,(1S-Trans)-(9Ci)
CAS No.	176242-19-6
Molecular Formula	C8H13NO2
Molecular Weight	155.19 g/mol
Synonyms	(1S,5S,7aS)-1-Methoxyhexahydro-1H-pyrrolizin-3(2H)-one; (1S-trans)-1-Methoxyhexahydro-3H-pyrrolizin-3-one; Hexahydro-1-methoxy-3H-pyrrolizin-3-one, (1S-trans)-; 176242-19-6; (1S,5S,7aR)-1-Methoxyoctahydropyrrolizin-3-one; (1S,5S,7aS)-1-Methoxyoctahydro-2H-pyrrolizin-3-one
EINECS	Contact for details

Quality Control

Our 3H-Pyrrolizin-3-One,Hexahydro-1-Methoxy-,(1S-Trans)-(9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.