Description

(S)-(4-Chlorophenyl)(Pyridin-2-Yl)Methanol is a high-purity chiral intermediate of significant importance in modern synthetic chemistry. This compound matters because it serves as a critical building block for the synthesis of enantiomerically pure pharmaceuticals and agrochemicals, where stereochemistry is crucial for biological activity. Pharmaceutical R&D departments and fine chemical manufacturers need it for developing active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring specific chiral configurations.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of enantiomerically pure Active Pharmaceutical Ingredients (APIs).
• Agrochemical Synthesis: Used in the research and production of chiral pesticides and herbicides.
• Ligand Precursor: Serves as a starting material for the preparation of chiral ligands used in asymmetric catalysis.
• Academic & Industrial Research: Valuable compound for methodological development in organic synthesis and medicinal chemistry.
• Fine Chemical Production: Intermediate for manufacturing other specialty chemicals requiring the (S)-configured benzhydrol moiety.

Basic Information

Product Name	(S)-(4-Chlorophenyl)(Pyridin-2-Yl)Methanol
CAS No.	176022-47-2
Molecular Formula	C12H10ClNO
Molecular Weight	219.67 g/mol
Synonyms	(S)-[4-Chlorophenyl](2-pyridinyl)methanol; (S)-α-(4-Chlorophenyl)-2-pyridinemethanol; (S)-2-Pyridyl(4-chlorophenyl)methanol; (S)-NSC 405124; (S)-Benzenemethanol, 4-chloro-α-(2-pyridinyl)-; (S)-Enantiomer of 4-Chloro-α-(2-pyridinyl)benzenemethanol; (S)-1-(4-Chlorophenyl)-1-(pyridin-2-yl)methanol
EINECS	Contact for details

Quality Control

Our (S)-(4-Chlorophenyl)(Pyridin-2-Yl)Methanol is produced under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as chiral purity (HPLC), chemical purity, and identity confirmation. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.