Description

1-(3-Hydroxypropyl)-5-[(2R)-2-[[2-[2-(2,2,2-Trifluoroethoxy)Phenoxy]Ethyl]Amino]Propyl]-1H-Indole-7-Carboxamide is a sophisticated, high-purity indole derivative with a defined stereocenter, representing a critical advanced intermediate in modern pharmaceutical synthesis. This compound is valued for its role in the research and development of targeted therapeutic agents, particularly those acting on specific receptor pathways. It is essential for pharmaceutical R&D teams, medicinal chemists, and fine chemical manufacturers engaged in creating novel drug candidates, especially within the fields of oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel, potent active pharmaceutical ingredients (APIs) for clinical research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Biochemical Tool Compound: Serves as a reference standard or probe in pharmacological assays to study specific biological targets and mechanisms.
• Preclinical Development: Employed in the scale-up synthesis of candidate compounds for toxicology and pharmacokinetic studies.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the biopharma industry.
• Academic Research: Utilized in university and institutional labs for cutting-edge research in organic synthesis and drug design.

Basic Information

Product Name	1-(3-Hydroxypropyl)-5-[(2R)-2-[[2-[2-(2,2,2-Trifluoroethoxy)Phenoxy]Ethyl]Amino]Propyl]-1H-Indole-7-Carboxamide
CAS No.	175870-21-0
Molecular Formula	C26H32F3N3O4
Molecular Weight	507.55 g/mol
Synonyms	5-[(2R)-2-[[2-[2-(2,2,2-Trifluoroethoxy)phenoxy]ethyl]amino]propyl]-1-(3-hydroxypropyl)-1H-indole-7-carboxamide; (R)-1-(3-Hydroxypropyl)-5-[2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]amino]propyl]indole-7-carboxamide; UNII-8KQ3JZJ5Q5; 8KQ3JZJ5Q5; BMS-204352 Carboxamide Derivative; (R)-BMS 204352 Carboxamide; 175870-21-0; A related intermediate of BMS-204352 (MaxiPost)
EINECS	Contact for details

Quality Control

This high-value intermediate is manufactured under strict quality management systems. Every batch is subjected to comprehensive analytical testing, including HPLC for purity and chiral integrity, NMR and MS for structural confirmation, and tests for residual solvents and moisture. We provide full traceability and detailed Certificates of Analysis (COA) to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture uptake, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.