Description

1H-Pyrrolo[2,1-D][1,2,5]Triazepine-1,5(2H)-Dione,Hexahydro-,(S)-(9Ci) is a high-purity, chiral heterocyclic compound with the CAS number 175853-35-7, serving as a critical advanced pharmaceutical intermediate (API) and a versatile building block in organic synthesis. Its value lies in its stereochemically defined structure, which is essential for developing enantiomerically pure active ingredients with targeted biological activity. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical sectors for the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key chiral building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Organic Synthesis Reagent: Used in constructing complex nitrogen-containing heterocycles for medicinal chemistry and material science applications.
• Asymmetric Catalysis Research: Serves as a precursor or ligand in the development of new catalytic systems for stereoselective reactions.
• Biochemical Research: Potential tool compound for studying enzyme inhibition and receptor-ligand interactions due to its specific stereochemistry.
• Fine Chemical Production: Intermediate for the manufacture of specialty chemicals requiring high enantiomeric purity.

Basic Information

Product Name	1H-Pyrrolo[2,1-D][1,2,5]Triazepine-1,5(2H)-Dione,Hexahydro-,(S)-(9Ci)
CAS No.	175853-35-7
Molecular Formula	C7H9N3O2
Molecular Weight	167.16 g/mol
Synonyms	(S)-Hexahydro-1H-pyrrolo[2,1-d][1,2,5]triazepine-1,5(2H)-dione; (S)-1,2,3,3a,4,7-Hexahydro-1H-pyrrolo[2,1-d][1,2,5]triazepine-1,5-dione; (S)-1,2,3,3a,4,7-Hexahydro-pyrrolo[2,1-d][1,2,5]triazepine-1,5-dione; (S)-Hexahydropyrrolotriazepinedione; (S)-HPTD; 175853-35-7; (S)-enantiomer of Hexahydro-1H-pyrrolo[2,1-d][1,2,5]triazepine-1,5(2H)-dione
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for advanced intermediates. Every batch is characterized and tested to confirm identity, purity, and chiral integrity. Certificates of Analysis (COA) are available upon request, detailing specifications such as assay, enantiomeric excess (ee), and impurity profiles. We adhere to a cGMP-compliant quality management system to ensure traceability and consistency for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product may be hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.