Description

2,8,9-Tri-I-Propyl-2,5,8,9-Tetraaza-1-Phosphabicyclo[3.3.3]Undecane is a sophisticated organophosphorus compound featuring a unique bicyclic cage structure, which imparts significant steric and electronic properties. This compound is valued as a highly effective ligand and catalyst precursor in advanced chemical synthesis, particularly for facilitating challenging coupling and polymerization reactions. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and materials science sectors for developing novel active ingredients and specialty polymers.

Application

• Catalyst Ligand in Cross-Coupling Reactions: Used as a specialized ligand for palladium, nickel, or other transition metal catalysts in Suzuki, Heck, and Negishi couplings for constructing complex organic molecules.
• Polymerization Catalyst Component: Serves as a co-catalyst or ligand in olefin polymerization and ring-opening polymerization (ROP) processes to control polymer tacticity and molecular weight.
• Pharmaceutical Intermediate Synthesis: Enables the synthesis of complex, sterically hindered intermediates in the development of new drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Research & Development: Employed in creating novel pesticide and herbicide molecules that require precise stereochemical control.
• Materials Science Research: Utilized in the development of metal-organic frameworks (MOFs), covalent organic frameworks (COFs), and other advanced functional materials.
• Asymmetric Synthesis: Acts as a chiral inducer or ligand in asymmetric catalytic reactions to produce enantiomerically pure compounds.
• Academic & Industrial R&D: A key reagent for methodological development in organic and organometallic chemistry laboratories worldwide.

Basic Information

Item	Details
Product Name	2,8,9-Tri-I-Propyl-2,5,8,9-Tetraaza-1-Phosphabicyclo[3.3.3]Undecane
CAS No.	175845-21-3
Molecular Formula	C18H39N4P
Molecular Weight	342.50 g/mol
Synonyms	Triisopropylphosphazene Cage Compound; 1,3,5-Triaza-7-phosphatricyclo[3.3.1.13,7]decane, 2,8,9-Tris(1-methylethyl)-; Verkade's Superbase (Triisopropyl derivative); P(i-PrNCH2CH2)3N; Tris(diisopropylamino)phosphazene; Proton Sponge® Analogue; 2,8,9-Triisopropyl-2,5,8,9-tetraaza-1-phosphabicyclo[3.3.3]undecane; TIPTAP
EINECS	Contact for details

Quality Control

Our production of 2,8,9-Tri-I-Propyl-2,5,8,9-Tetraaza-1-Phosphabicyclo[3.3.3]Undecane adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high purity. All products undergo rigorous analytical testing, including NMR (¹H, ¹³C, ³¹P), HPLC, and elemental analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.