Description

1-Acetyl-5-(2-Aminopropyl)-2,3-Dihydro-1H-Indole-7-Carbonitrile is a high-purity, synthetically versatile indole derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate and a valuable building block for medicinal chemistry research, enabling the development of novel therapeutic agents. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Serves as a building block for creating new active ingredients with potential insecticidal or herbicidal properties.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals and dyes.
• Academic Research: Utilized in universities and research institutes for studying indole chemistry and developing new synthetic methodologies.
• Contract Manufacturing (CMO/CDMO): Supplied to contract research and manufacturing organizations for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	1-Acetyl-5-(2-Aminopropyl)-2,3-Dihydro-1H-Indole-7-Carbonitrile
CAS No.	175837-01-1
Molecular Formula	C₁₄H₁₇N₃O
Molecular Weight	243.31 g/mol
Synonyms	7-Cyano-1-acetyl-5-(2-aminopropyl)-2,3-dihydro-1H-indole; 5-(2-Aminopropyl)-1-acetyl-2,3-dihydro-1H-indole-7-carbonitrile; 1H-Indole-7-carbonitrile, 1-acetyl-5-(2-aminopropyl)-2,3-dihydro-; AKOS BRN 0970; 1-Acetyl-5-(2-aminopropyl)indoline-7-carbonitrile; ZINC000103074583; ACH-00001352; BCP31932
EINECS	Contact for details

Quality Control

Our production of 1-Acetyl-5-(2-Aminopropyl)-2,3-Dihydro-1H-Indole-7-Carbonitrile adheres to stringent internal quality standards, ensuring batch-to-batch consistency and high purity suitable for research and development. All materials are characterized by advanced analytical techniques including HPLC, GC-MS, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in a desiccated environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.