Description

2-(Dichloromethyl)-3-Nitrothiophene is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its unique molecular architecture, featuring both a reactive dichloromethyl group and a nitro-substituted thiophene ring, enabling its use in constructing complex pharmacophores and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and electronic materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides and fungicides, leveraging the bioactivity of the nitro-thiophene scaffold.
• Material Science Research: Serves as a monomer or building block for conducting polymers and organic semiconductors due to the electron-accepting nitro group on the thiophene core.
• Chemical Research: Employed in methodological studies for palladium-catalyzed cross-coupling reactions and other transformations involving halogenated heterocycles.
• Dye and Pigment Intermediate: Acts as a starting material for synthesizing specialized chromophores and pigments with specific light-absorption properties.

Basic Information

Product Name	2-(Dichloromethyl)-3-Nitrothiophene
CAS No.	175731-00-7
Molecular Formula	C5H3Cl2NO2S
Molecular Weight	212.05 g/mol
Synonyms	3-Nitro-2-(dichloromethyl)thiophene; 2-(Dichloromethyl)-3-nitrothiophene; Thiophene, 2-(dichloromethyl)-3-nitro-; 175731-00-7; 3-Nitro-2-dichloromethylthiophene; 2-Dichloromethyl-3-nitrothiophene
EINECS	Contact for details

Quality Control

Our 2-(Dichloromethyl)-3-Nitrothiophene is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to the reactive functional groups, it is recommended to store under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.