Description

4-(3-Chloro-4-Methylphenyl)-5-Methyl-1,3-Thiazol-2-Amine is a high-purity, specialized organic intermediate featuring a functionalized thiazole core. This compound matters for its role as a critical building block in the synthesis of advanced pharmaceutical and agrochemical agents, enabling the development of novel bioactive molecules. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Serves as a core structural component in the development of new herbicides, fungicides, or insecticides.
• Chemical Research & Development: Used as a versatile building block for constructing complex heterocyclic compounds in medicinal and synthetic chemistry.
• Material Science: Potential monomer or additive for creating specialized polymers with unique electronic or optical properties.
• Bioconjugation & Probe Development: The amine functional group allows for conjugation, making it useful in developing biochemical probes or diagnostic agents.

Basic Information

Product Name	4-(3-Chloro-4-Methylphenyl)-5-Methyl-1,3-Thiazol-2-Amine
CAS No.	175278-40-7
Molecular Formula	C11H11ClN2S
Molecular Weight	238.73 g/mol
Synonyms	2-Amino-4-(3-chloro-4-methylphenyl)-5-methylthiazole; 5-Methyl-4-(3-chloro-4-methylphenyl)-2-thiazolamine; 4-(3-Chloro-4-methylphenyl)-5-methyl-2-thiazolamine; 4-(3-Chloro-p-tolyl)-5-methyl-1,3-thiazol-2-amine; 2-Thiazolamine, 4-(3-chloro-4-methylphenyl)-5-methyl-; 175278-40-7; AKOS BRN 0971
EINECS	Contact for details

Quality Control

Our 4-(3-Chloro-4-Methylphenyl)-5-Methyl-1,3-Thiazol-2-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.