Description

2-(Trifluoromethoxy)Thiophenol is a specialized organosulfur compound featuring a thiol group and a trifluoromethoxy substituent on an aromatic ring. This unique structure makes it a valuable building block in advanced chemical synthesis, particularly for introducing sulfur and fluorine-containing motifs. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing drug candidates, especially those requiring bioisosteric replacement or enhanced metabolic stability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the trifluoromethoxy group improves efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science: Incorporated into polymers and advanced materials to impart specific surface properties or reactivity.
• Custom Synthesis and R&D: Employed in research laboratories for method development and the exploration of new chemical entities.

Basic Information

Product Name	2-(Trifluoromethoxy)Thiophenol
CAS No.	175278-01-0
Molecular Formula	C7H5F3OS
Molecular Weight	194.17 g/mol
Synonyms	2-(Trifluoromethoxy)benzenethiol; o-(Trifluoromethoxy)thiophenol; 2-(Trifluoromethoxy)phenyl mercaptan; 1-(Trifluoromethoxy)-2-mercaptobenzene; 2-Mercaptophenyl trifluoromethyl ether; α-(Trifluoromethoxy)thiophenol; Benzenethiol, 2-(trifluoromethoxy)-; CAS 175278-01-0
EINECS	Contact for details

Quality Control

Every batch of 2-(Trifluoromethoxy)Thiophenol is produced and tested under strict quality management protocols to ensure consistency and purity for demanding synthetic applications. Our products undergo rigorous quality testing, including chromatographic purity analysis and identity confirmation, to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed batch-specific data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, well-ventilated area. Due to its sensitivity, keep away from strong oxidizing agents and minimize exposure to air.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.