Description

L-2-Aminobutyric Acid D1 is a high-purity, isotopically labeled amino acid derivative, specifically deuterated at the alpha position. This compound is a critical building block for advanced research and development, offering enhanced stability and traceability in analytical applications. It is primarily utilized by pharmaceutical researchers, analytical chemists, and life science companies engaged in metabolic studies, drug discovery, and the development of internal standards for mass spectrometry.

Application

• Internal Standard for Mass Spectrometry (MS): Serves as a stable, non-interfering reference compound for the precise quantification of endogenous L-2-aminobutyric acid and related metabolites in complex biological matrices.
• Metabolic Pathway Tracing: Used in deuterium-labeling studies to investigate amino acid metabolism, protein turnover, and biochemical pathways in vivo and in vitro.
• Pharmaceutical Reference Standard: Employed as a certified reference material (CRM) for method development, validation, and quality control in drug substance and product analysis.
• Biochemical Research: Acts as a precursor or intermediate in the synthesis of more complex labeled peptides, probes, or potential therapeutic agents.
• Nutraceutical & Cosmetic Research: Applied in stability and bioavailability studies of products containing amino acid derivatives.

Basic Information

Product Name	L-2-Aminobutyric Acid D1
CAS No.	175274-24-5
Molecular Formula	C4H8DNO2
Molecular Weight	104.13 g/mol (for monoisotopic)
Synonyms	(2S)-2-Amino[2-2H]butanoic acid; L-α-Aminobutyric acid-d1; (S)-2-Aminobutyric-2-d acid; L-2-Aminobutyric-2-d acid; Deuterated L-2-aminobutyrate; L-Homoalanine-d1; ABA-d1; 2-AB-d1
EINECS	Contact for details

Quality Control

Our L-2-Aminobutyric Acid D1 is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity, isotopic enrichment (D-content), and chemical purity assessments via advanced techniques like HPLC, NMR, and MS. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Isotopic Enrichment (MS)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.