Description

5-(Methylthio)Thiophene-2-Carbonitrile is a high-purity, sulfur-containing heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a versatile precursor for the development of novel pharmaceuticals, agrochemicals, and functional materials due to its unique thiophene core and reactive nitrile and methylthio functional groups. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Research: Serves as a crucial building block for developing new generation herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Used in the research and production of conductive polymers, organic semiconductors, and non-linear optical (NLO) materials.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and organocatalysts.
• Dye & Pigment Synthesis: Acts as an intermediate in the manufacture of specialized dyes and pigments for high-performance applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke chemical synthesis and scale-up projects.

Basic Information

Product Name	5-(Methylthio)Thiophene-2-Carbonitrile
CAS No.	175205-78-4
Molecular Formula	C6H5NS2
Molecular Weight	155.24 g/mol
Synonyms	2-Cyano-5-(methylthio)thiophene; 5-Methylsulfanylthiophene-2-carbonitrile; Thiophene-2-carbonitrile, 5-(methylthio)-; 5-(Methylmercapto)thiophene-2-carbonitrile; 5-Methylthio-2-cyanothiophene; 2-Thiophenecarbonitrile, 5-(methylthio)-; 5-Methylsulfanyl-2-thiophenecarbonitrile
EINECS	Contact for details

Quality Control

Our 5-(Methylthio)Thiophene-2-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for sensitive R&D and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.