Description

3-Bromo-5-Chlorothiophene-2-Sulfonyl Chloride is a high-purity, multi-functional organosulfur building block essential for advanced chemical synthesis. This compound matters because its reactive sulfonyl chloride and halogenated thiophene structure enables precise molecular construction in complex organic frameworks. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science Research: Serves as a monomer or cross-linking agent for creating conductive polymers, organic semiconductors, and specialty polymers with unique electronic properties.
• Chemical Biology Probes: Employed in the design and synthesis of activity-based probes (ABPs) and covalent inhibitors for studying enzyme function and drug discovery.
• Ligand and Catalyst Development: Acts as a versatile scaffold for constructing complex ligands used in transition metal catalysis and asymmetric synthesis.
• Custom Synthesis and Contract Manufacturing: A critical raw material for fine chemical companies offering bespoke synthesis services for clients in regulated industries.

Basic Information

Product Name	3-Bromo-5-Chlorothiophene-2-Sulfonyl Chloride
CAS No.	175205-72-8
Molecular Formula	C4HBrCl2O2S2
Molecular Weight	300.00 g/mol
Synonyms	2-Thiophenesulfonyl chloride, 3-bromo-5-chloro-; 3-Bromo-5-chloro-2-thiophenesulfonyl chloride; 3-Bromo-5-chlorothiophene-2-sulfonyl chloride; 5-Chloro-3-bromothiophene-2-sulfonyl chloride; 3-Bromo-5-chlorothiophene-2-sulphonyl chloride; 3-Bromo-5-chloro-thiophene-2-sulfonylchloride; 3-Bromo-5-chloro-thiophene-2-sulfonyl chloride; 175205-72-8
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Chlorothiophene-2-Sulfonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to traceability and documentation supports our clients' needs for regulatory compliance in pharmaceutical and agrochemical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.