Description

4-Bromo-2-(2-Nitroprop-1-Enyl)Thiophene is a specialized heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, which combines a brominated thiophene ring with a nitroalkene moiety, enabling precise functionalization and the construction of complex molecular frameworks. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it serves as a key intermediate for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its thiophene-based structure for bioactivity.
• Material Science Research: Serves as a monomer or building block for the development of advanced organic electronic materials, such as conductive polymers and organic semiconductors.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological processes and enzyme mechanisms.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to create complex biaryl systems.
• Nitroalkene Chemistry: The nitropropene group is a versatile handle for further transformations, including Michael additions and reductions to amine functionalities.

Basic Information

Product Name	4-Bromo-2-(2-Nitroprop-1-Enyl)Thiophene
CAS No.	175205-19-3
Molecular Formula	C7H6BrNO2S
Molecular Weight	248.10 g/mol
Synonyms	4-Bromo-2-(2-nitroprop-1-en-1-yl)thiophene; 2-(2-Nitroprop-1-enyl)-4-bromothiophene; Thiophene, 4-bromo-2-(2-nitro-1-propenyl)-; 4-Bromo-2-(2-nitropropenyl)thiophene; 175205-19-3; 4-Bromo-2-(2-nitroprop-1-enyl)thiophene
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-(2-Nitroprop-1-Enyl)Thiophene is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We employ advanced analytical techniques, including HPLC, GC, NMR, and mass spectrometry, for comprehensive characterization and purity verification. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.