Description

2-(Then-3-Yl)Thioacetamide is a specialized heterocyclic organic compound featuring a thiophene moiety linked to a thioacetamide group, serving as a valuable synthetic intermediate and building block in advanced chemical synthesis. Its unique molecular architecture makes it a critical precursor for developing novel pharmaceuticals, agrochemicals, and functional materials where specific sulfur-containing heterocycles are required. This high-purity intermediate is essential for research and development chemists and process scale-up teams in the pharmaceutical, agrochemical, and material science industries seeking to innovate and optimize complex synthetic routes.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that leverage the bioactivity of the thiophene-thioacetamide structure.
• Material Science Research: Acts as a monomer or precursor in the development of advanced polymers, organic semiconductors, and conductive materials with tailored electronic properties.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalysis, facilitating more efficient and selective chemical transformations.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis for high-throughput screening.

Basic Information

Product Name	2-(Then-3-Yl)Thioacetamide
CAS No.	175203-99-3
Molecular Formula	C7H7NOS2
Molecular Weight	185.27 g/mol
Synonyms	2-(Thiophen-3-yl)thioacetamide; 3-Thienylthioacetamide; N-(3-Thienyl)thioacetamide; 2-(3-Thienylthio)acetamide; Thioacetamide, 2-(3-thienyl)-; 175203-99-3; 2-(Then-3-yl)thioacetamide
EINECS	Contact for details

Quality Control

Our 2-(Then-3-Yl)Thioacetamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support compliance with cGMP, ICH Q7, and REACH regulations for our global clientele.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. The compound may be hygroscopic; handle and store under an inert atmosphere such as nitrogen for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.