Description

Ethyl 5-(Trifluoromethoxy)Indole-2-Carboxylate is a high-value, multi-functional indole derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring both an indole core and a trifluoromethoxy substituent, makes it an essential intermediate for creating compounds with tailored biological and physical properties. This product is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the trifluoromethoxy group can enhance metabolic stability and bioavailability.
• Material Science: Serves as a monomer or functional additive in the research of specialty polymers and advanced organic electronic materials.
• Chemical Synthesis: An important reagent for constructing complex heterocyclic frameworks in academic and industrial organic chemistry laboratories.
• Biochemical Probe Development: Utilized in medicinal chemistry to create molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	Ethyl 5-(Trifluoromethoxy)Indole-2-Carboxylate
CAS No.	175203-82-4
Molecular Formula	C12H10F3NO3
Molecular Weight	273.21 g/mol
Synonyms	5-(Trifluoromethoxy)-1H-indole-2-carboxylic acid ethyl ester; Ethyl 5-(trifluoromethoxy)-1H-indole-2-carboxylate; 1H-Indole-2-carboxylic acid, 5-(trifluoromethoxy)-, ethyl ester; 5-Trifluoromethoxyindole-2-carboxylic acid ethyl ester; 2-Carbethoxy-5-trifluoromethoxyindole; Ethyl 5-trifluoromethoxyindole-2-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 5-(Trifluoromethoxy)Indole-2-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards, and specifications can be tailored to meet specific research or cGMP starting material requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed and under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.