Description

Methyl 4-Chloro-6-(Trifluoromethyl)Thieno[3,4-B]-Pyridine-1-Carboxylate is a high-value, heterocyclic organic compound featuring a fused thienopyridine core, strategically functionalized with chloro and trifluoromethyl groups. This molecular architecture makes it a critical advanced pharmaceutical intermediate (API) for the synthesis of novel, high-potency active ingredients. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and material science sectors for constructing complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in oncology, antiviral, and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Serves as a precursor for developing new-generation pesticides and herbicides, leveraging the bioactivity of the thienopyridine scaffold.
• Material Science Precursor: Used in the research and development of specialty chemicals and functional materials, including organic semiconductors and ligands for catalysis.
• Chemical Synthesis: An essential reagent for medicinal and process chemists in constructing complex heterocyclic systems for structure-activity relationship (SAR) studies.

Basic Information

Product Name	Methyl 4-Chloro-6-(Trifluoromethyl)Thieno[3,4-B]-Pyridine-1-Carboxylate
CAS No.	175203-40-4
Molecular Formula	C11H5ClF3NO2S
Molecular Weight	307.67 g/mol
Synonyms	Methyl 4-chloro-6-(trifluoromethyl)thieno[3,4-b]pyridine-1-carboxylate; 4-Chloro-6-(trifluoromethyl)thieno[3,4-b]pyridine-1-carboxylic acid methyl ester; 1-Carbomethoxy-4-chloro-6-trifluoromethylthieno[3,4-b]pyridine; Thieno[3,4-b]pyridine-1-carboxylic acid, 4-chloro-6-(trifluoromethyl)-, methyl ester; CAS 175203-40-4
EINECS	Contact for details

Quality Control

Every batch of our Methyl 4-Chloro-6-(Trifluoromethyl)Thieno[3,4-B]-Pyridine-1-Carboxylate is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency meet the exacting standards required for research and development. A detailed Certificate of Analysis (COA) is available for each lot, confirming specifications for assay and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.