Description

2-[1-Methyl-3-(Trifluoromethyl)Pyrazol-5-Yl]-Thiophene-5-Carboxylic Acid CAS NO 175202-29-6 is a high-purity heterocyclic carboxylic acid building block featuring a unique trifluoromethylpyrazole-thiophene hybrid structure. This compound is valued for its role as a critical synthetic intermediate in advanced organic synthesis, particularly in the development of novel active ingredients. It is primarily sought by R&D and production teams in the pharmaceutical and agrochemical industries for creating new molecules with enhanced biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of new drug candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents, including herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethylpyrazole moiety.
• Material Science Research: Serves as a precursor for functional materials, such as organic semiconductors or ligands for metal-organic frameworks (MOFs), due to its conjugated thiophene-carboxylic acid system.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specialized fluorinated heterocycles.

Basic Information

Product Name	2-[1-Methyl-3-(Trifluoromethyl)Pyrazol-5-Yl]-Thiophene-5-Carboxylic Acid
CAS No.	175202-29-6
Molecular Formula	C10H7F3N2O2S
Molecular Weight	276.24 g/mol
Synonyms	5-(1-Methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl)thiophene-2-carboxylic acid; 2-(1-Methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl)thiophene-5-carboxylic acid; Thiophene-5-carboxylic acid, 2-[1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl]-; 175202-29-6; 5-(1-Methyl-3-(trifluoromethyl)pyrazol-5-yl)thiophene-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 2-[1-Methyl-3-(Trifluoromethyl)Pyrazol-5-Yl]-Thiophene-5-Carboxylic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure consistency and meet exacting customer specifications. Certificates of Analysis (COA) documenting all critical quality attributes are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.