Description

Methyl 4-(Isopropylsulfonyl)-3-(1H-Pyrrol-1-Yl)Thiophene-2-Carboxylate is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. This compound is engineered to serve as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and specialty agrochemicals. Its unique molecular architecture, featuring a thiophene core with sulfonyl and pyrrole substituents, makes it an essential material for research and production chemists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to introduce complex functionality into their target molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-inflammatory agents, and kinase inhibitors.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the thiophene and pyrrole motifs contribute to biological activity.
• Material Science Research: Serves as a precursor for the development of organic semiconductors, conductive polymers, and advanced organic electronic materials due to its electron-rich heterocyclic system.
• Chemical Biology Probes: Employed in the creation of specialized molecular probes and tags for studying biological processes and enzyme mechanisms.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing complex molecules for clients.
• Academic & Industrial R&D: Facilitates exploratory chemistry in university and corporate R&D laboratories focused on heterocyclic chemistry and method development.

Basic Information

Product Name	Methyl 4-(Isopropylsulfonyl)-3-(1H-Pyrrol-1-Yl)Thiophene-2-Carboxylate
CAS No.	175201-79-3
Molecular Formula	C13H15NO4S2
Molecular Weight	313.39 g/mol
Synonyms	Methyl 4-(1-methylethylsulfonyl)-3-(1H-pyrrol-1-yl)thiophene-2-carboxylate; 2-Thiophenecarboxylic acid, 4-[(1-methylethyl)sulfonyl]-3-(1H-pyrrol-1-yl)-, methyl ester; 4-Isopropylsulfonyl-3-pyrrol-1-yl-thiophene-2-carboxylic acid methyl ester; 3-(1H-Pyrrol-1-yl)-4-(isopropylsulfonyl)thiophene-2-carboxylic acid methyl ester; Methyl 3-(pyrrol-1-yl)-4-(isopropylsulfonyl)thiophene-2-carboxylate; 175201-79-3; Methyl 4-(propan-2-ylsulfonyl)-3-(1H-pyrrol-1-yl)thiophene-2-carboxylate
EINECS	Contact for details

Quality Control

Our production of Methyl 4-(Isopropylsulfonyl)-3-(1H-Pyrrol-1-Yl)Thiophene-2-Carboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and MS for identity verification. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP (current Good Manufacturing Practice) standards for pharmaceutical-grade material upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.