Description

Methyl 4-[(4-Chlorophenyl)Sulfonyl]-3-Methylthiophene-2-Carboxylate is a high-purity, synthetically valuable sulfonyl-substituted thiophene derivative. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in organic synthesis, enabling the development of novel active molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new compounds with targeted biological activities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used as a building block for developing new generation herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science: Serves as a monomer or functional additive in the research of advanced polymers and organic electronic materials due to its conjugated thiophene core.
• Organic Synthesis: A versatile reagent for constructing complex heterocyclic systems via cross-coupling reactions, nucleophilic substitutions, and other transformations.
• Chemical Biology: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biochemical research and target validation.

Basic Information

Product Name	Methyl 4-[(4-Chlorophenyl)Sulfonyl]-3-Methylthiophene-2-Carboxylate
CAS No.	175137-60-7
Molecular Formula	C13H11ClO4S2
Molecular Weight	330.80 g/mol
Synonyms	Methyl 4-[(4-chlorophenyl)sulfonyl]-3-methyl-2-thiophenecarboxylate; 3-Methyl-4-[(4-chlorophenyl)sulfonyl]thiophene-2-carboxylic acid methyl ester; 2-Thiophenecarboxylic acid, 4-[(4-chlorophenyl)sulfonyl]-3-methyl-, methyl ester; Methyl 3-methyl-4-(4-chlorophenylsulfonyl)thiophene-2-carboxylate; 4-(4-Chlorobenzenesulfonyl)-3-methylthiophene-2-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 4-[(4-Chlorophenyl)Sulfonyl]-3-Methylthiophene-2-Carboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all specifications and test results to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. The container must be kept tightly sealed to protect the product from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.