Description

Methyl 3-Chloro-4-Methylthiophene-2-Carboxylate is a high-purity, synthetically valuable heterocyclic building block. This compound serves as a critical intermediate in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily utilized by research and development chemists and process scale-up teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Building block for developing new-generation herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science Research: Used in the development of organic semiconductors, conductive polymers, and advanced electronic materials due to its thiophene core.
• Chemical Research & Development: Versatile scaffold for medicinal chemistry, facilitating structure-activity relationship (SAR) studies and library synthesis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP guidelines.

Basic Information

Product Name	Methyl 3-Chloro-4-Methylthiophene-2-Carboxylate
CAS No.	175137-11-8
Molecular Formula	C8H7ClO2S
Molecular Weight	202.65 g/mol
Synonyms	Methyl 3-chloro-4-methylthiophene-2-carboxylate; 3-Chloro-4-methylthiophene-2-carboxylic acid methyl ester; 2-Thiophenecarboxylic acid, 3-chloro-4-methyl-, methyl ester; Methyl 3-chloro-4-methyl-2-thiophenecarboxylate; 3-Chloro-4-methyl-2-thiophenecarboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 3-Chloro-4-Methylthiophene-2-Carboxylate adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.