Description

Methyl 3-Amino-5-(4-Fluorophenyl)Thiophene-2-Carboxylate is a high-value heterocyclic building block featuring both amino and ester functional groups on a thiophene core. This compound is critical for the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiophene scaffold.
• Material Science: Serves as a monomer or building block for creating conjugated polymers and organic electronic materials due to its electron-rich thiophene structure.
• Chemical Synthesis: Utilized in medicinal chemistry for parallel synthesis and combinatorial chemistry to generate diverse compound libraries for screening.
• Dye & Pigment Intermediate: Acts as a starting material for synthesizing specialized dyes and pigments where the fluorophenyl group influences color and stability.

Basic Information

Product Name	Methyl 3-Amino-5-(4-Fluorophenyl)Thiophene-2-Carboxylate
CAS No.	175137-08-3
Molecular Formula	C12H10FNO2S
Molecular Weight	251.28 g/mol
Synonyms	Methyl 3-amino-5-(4-fluorophenyl)thiophene-2-carboxylate; 3-Amino-5-(4-fluorophenyl)thiophene-2-carboxylic acid methyl ester; 2-Thiophenecarboxylic acid, 3-amino-5-(4-fluorophenyl)-, methyl ester; Methyl 3-amino-5-(p-fluorophenyl)thiophene-2-carboxylate; 5-(4-Fluorophenyl)-3-aminothiophene-2-carboxylic acid methyl ester; 175137-08-3; MFCD11053619
EINECS	Contact for details

Quality Control

Our production of Methyl 3-Amino-5-(4-Fluorophenyl)Thiophene-2-Carboxylate adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and scale-up applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support cGMP-compliant manufacturing for advanced projects requiring rigorous documentation and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.