Description

Methyl 3-Amino-5-(Thien-3-Yl)Thiophene-2-Carboxylate is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, which combines amino and ester functionalities with a bithiophene core, making it a versatile precursor for constructing complex molecular frameworks. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it serves as a key intermediate for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in the development of compounds targeting central nervous system (CNS) disorders, anti-infectives, and oncology therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its thiophene-based structure contributes to biological activity.
• Organic Electronic Materials: Serves as a precursor for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs), organic photovoltaics (OPVs), and field-effect transistors (OFETs).
• Dye and Pigment Chemistry: Acts as an intermediate in the synthesis of specialized dyes and functional pigments due to its electron-rich thiophene system.
• Ligand and Catalyst Development: The amino group provides a handle for coordination chemistry, useful in creating novel ligands for catalytic systems.
• Chemical Research & Development: A valuable tool for academic and industrial R&D focused on heterocyclic chemistry, material science, and medicinal chemistry.

Basic Information

Product Name	Methyl 3-Amino-5-(Thien-3-Yl)Thiophene-2-Carboxylate
CAS No.	175137-07-2
Molecular Formula	C10H9NO2S2
Molecular Weight	239.31 g/mol
Synonyms	Methyl 3-amino-5-(3-thienyl)thiophene-2-carboxylate; 3-Amino-5-(3-thienyl)thiophene-2-carboxylic acid methyl ester; 2-Thiophenecarboxylic acid, 3-amino-5-(3-thienyl)-, methyl ester; Methyl 3-amino-5-(thiophen-3-yl)thiophene-2-carboxylate; 175137-07-2; 3-Thiopheneacetic acid, α-amino-5-(3-thienyl)-, methyl ester (tautomeric form).
EINECS	Contact for details

Quality Control

Our Methyl 3-Amino-5-(Thien-3-Yl)Thiophene-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance in cGMP and ISO 9001 environments for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.