Description

3-Amino-5-(4-Chlorophenyl)Thiophene-2-Carboxamide is a high-value heterocyclic building block and pharmaceutical intermediate of significant commercial interest. Its molecular structure, featuring both amino and carboxamide functional groups on a thiophene core, makes it a versatile precursor for synthesizing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients. Its reliable synthesis and consistent purity are critical for downstream process efficiency and final product quality.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel drug candidates, particularly in therapeutic areas targeting central nervous system disorders, inflammation, and oncology.
• Agrochemical Synthesis: Serves as a core structure for developing advanced pesticides, herbicides, and fungicides, leveraging the bioactivity of the thiophene and chlorophenyl motifs.
• Organic Light-Emitting Diode (OLED) Materials: Used in the research of organic electronic materials, where its conjugated system can contribute to charge transport properties.
• Dye and Pigment Intermediate: Acts as a precursor for synthesizing specialized dyes and pigments due to its ability to form complex, colored heterocyclic systems.
• Chemical Research & Development: Employed as a standard or building block in academic and industrial R&D for methodological studies and library synthesis.
• Ligand for Catalysis: The amino and carboxamide groups can be modified to create novel ligands for metal-catalyzed reactions.

Basic Information

Product Name	3-Amino-5-(4-Chlorophenyl)Thiophene-2-Carboxamide
CAS No.	175137-05-0
Molecular Formula	C11H9ClN2OS
Molecular Weight	252.72 g/mol
Synonyms	3-Amino-5-(4-chlorophenyl)thiophene-2-carboxamide; 2-Thiophenecarboxamide, 3-amino-5-(4-chlorophenyl)-; 5-(4-Chlorophenyl)-3-aminothiophene-2-carboxamide; 3-Amino-5-(p-chlorophenyl)thiophene-2-carboxylic acid amide; 175137-05-0; AKOS BBS-00004319; CTK8G0335; NSC 405124; ZINC000003869756; AMY40313
EINECS	Contact for details

Quality Control

Our 3-Amino-5-(4-Chlorophenyl)Thiophene-2-Carboxamide is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical and advanced chemical synthesis. Certificates of Analysis (COA) detailing all relevant specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to brown powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.