Description

4-Bromo-6-(Trifluoromethyl)Benzimidazole-2-Thiol is a high-value, multi-functional heterocyclic building block characterized by its bromo and trifluoromethyl substituents. This compound matters for its role as a critical intermediate in the synthesis of advanced pharmaceuticals and agrochemicals, where it imparts desirable biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in creating advanced herbicides and fungicides, leveraging the bioactivity of the benzimidazole-thiol core.
• Material Science Precursor: Serves as a building block for organic electronic materials and metal-organic frameworks (MOFs).
• Chemical Research & Development: Employed in academic and industrial labs for exploring new heterocyclic chemistry and reaction pathways.
• Ligand Synthesis: Useful for preparing specialized ligands in coordination chemistry and catalysis.

Basic Information

Product Name	4-Bromo-6-(Trifluoromethyl)Benzimidazole-2-Thiol
CAS No.	175135-17-8
Molecular Formula	C8H4BrF3N2S
Molecular Weight	297.10 g/mol
Synonyms	4-Bromo-6-(trifluoromethyl)-1H-benzimidazole-2-thiol; 2-Mercapto-4-bromo-6-(trifluoromethyl)benzimidazole; 4-Bromo-6-trifluoromethyl-2-mercaptobenzimidazole; 175135-17-8; 4-Bromo-6-(trifluoromethyl)-2-benzimidazolethiol; 4-Bromo-6-(trifluoromethyl)-2-mercaptobenzimidazole; 2-Benzimidazolethiol, 4-bromo-6-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 4-Bromo-6-(Trifluoromethyl)Benzimidazole-2-Thiol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is light-sensitive and should be stored away from light. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.