Description

2-Bromo-1,3-Dichloro-5-Methoxybenzene is a high-purity halogenated aromatic building block of significant importance in advanced organic synthesis. This compound serves as a critical intermediate for constructing complex molecular architectures, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought after by R&D chemists and process development scientists for applications in cross-coupling reactions and the synthesis of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), especially those requiring a specific halogenated aromatic core.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where its substitution pattern imparts specific biological activity.
• Material Science Research: Serves as a monomer or precursor in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An effective substrate in Suzuki, Stille, and Buchwald-Hartwig amination reactions for creating complex biaryl and heteroaryl structures.
• Chemical Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and validation.
• Organic Synthesis Building Block: Employed in academic and industrial research for the construction of complex natural products and novel chemical entities.

Basic Information

Product Name	2-Bromo-1,3-Dichloro-5-Methoxybenzene
CAS No.	174913-20-3
Molecular Formula	C7H5BrCl2O
Molecular Weight	256.92 g/mol
Synonyms	1-Bromo-2,4-dichloro-5-methoxybenzene; 2,4-Dichloro-5-methoxybromobenzene; 5-Methoxy-2,4-dichlorobromobenzene; Benzene, 2-bromo-1,3-dichloro-5-methoxy-; 2-Bromo-5-methoxy-1,3-dichlorobenzene
EINECS	Contact for details

Quality Control

Our 2-Bromo-1,3-Dichloro-5-Methoxybenzene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, assay, and impurity profiles. We support our clients' regulatory needs with full traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.