Description

1-Chloro-8-methylisoquinoline is a versatile halogenated isoquinoline derivative, a crucial building block in advanced organic synthesis. Its value lies in providing a functionalized scaffold for constructing complex molecules, particularly in the development of pharmaceuticals and agrochemicals. This compound is essential for research chemists and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, especially those targeting neurological disorders or exhibiting antimicrobial activity.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the biological activity of the isoquinoline core.
• Ligand and Catalyst Development: Acts as a starting material for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or light-emitting components.
• Chemical Biology Probes: Utilized to develop molecular probes for studying enzyme function and biological pathways.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic chemistry and novel heterocycle construction.

Basic Information

Item	Details
Product Name	1-Chloro-8-methylisoquinoline
CAS No.	174873-81-5
Molecular Formula	C10H8ClN
Molecular Weight	177.63 g/mol
Synonyms	8-Methyl-1-chloroisoquinoline; 1-Chloro-8-methyl-isoquinoline; Isoquinoline, 1-chloro-8-methyl-; 1-Chloro-8-methylisoquinoline; 174873-81-5; 8-Methyl-1-chloro-isoquinoline; 1-Chloro-8-methyl-isoquinoline
EINECS	Contact for details

Quality Control

Our 1-Chloro-8-methylisoquinoline is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.