Description

Cyclohexanethiol,5-Methyl-2-(1-Methylethyl)-,(1R,2R,5S)-(9Ci) is a high-purity, chiral thiol derivative of menthol, characterized by its specific stereochemistry. This compound is a valuable chiral building block and ligand precursor, offering unique reactivity and selectivity in asymmetric synthesis. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and fine chemical sectors for developing novel active ingredients and catalysts.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of complex drug molecules, particularly those requiring specific stereocenters.
• Catalyst Ligand Precursor: Used to develop novel chiral ligands for transition metal catalysis in asymmetric hydrogenation and carbon-carbon bond formation.
• Agrochemical Research: Employed in the research and development of new chiral pesticides and herbicides where stereochemistry impacts biological activity.
• Fine Chemical Synthesis: Acts as a building block for fragrances, flavors, and other specialty chemicals that benefit from its menthol-related structure and thiol functionality.
• Material Science: Investigated for use in surface modification and as a component in advanced polymeric materials.

Basic Information

Product Name	Cyclohexanethiol,5-Methyl-2-(1-Methylethyl)-,(1R,2R,5S)-(9Ci)
CAS No.	174757-27-8
Molecular Formula	C10H20S
Molecular Weight	172.33 g/mol
Synonyms	(1R,2R,5S)-5-Methyl-2-(1-methylethyl)cyclohexanethiol; (-)-Menthyl Mercaptan; (1R,2R,5S)-(-)-Menthyl Mercaptan; (1R,2R,5S)-2-Isopropyl-5-methylcyclohexanethiol; L-Menthyl Mercaptan; (1R,2R,5S)-Thiomenthol
EINECS	Contact for details

Quality Control

Our production of Cyclohexanethiol,5-Methyl-2-(1-Methylethyl)-,(1R,2R,5S)-(9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC, GC, and NMR, to verify identity, purity, and stereochemical integrity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.