Description

5-Methoxy-2-Trifluoromethylindole is a high-purity, specialized indole derivative characterized by its methoxy and trifluoromethyl substituents, which confer unique electronic and steric properties. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block for the synthesis of complex organic molecules. It is essential for research and development teams in the pharmaceutical, agrochemical, and material science industries seeking to develop novel active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of new-generation pesticides and herbicides due to the bioactivity of the indole scaffold.
• Material Science Research: Serves as a building block for organic electronic materials and functional dyes.
• Chemical Biology: Employed as a probe or ligand in the study of biological pathways and protein interactions.
• Academic & R&D: A valuable reagent for methodological development in organic synthesis and catalysis studies.
• Custom Synthesis: The starting point for the contract manufacturing of complex, fluorinated specialty chemicals.

Basic Information

Product Name	5-Methoxy-2-Trifluoromethylindole
CAS No.	174734-34-0
Molecular Formula	C10H8F3NO
Molecular Weight	215.17 g/mol
Synonyms	2-(Trifluoromethyl)-5-methoxy-1H-indole; 5-Methoxy-2-(trifluoromethyl)-1H-indole; 1H-Indole, 5-methoxy-2-(trifluoromethyl)-; 5-Methoxy-2-trifluoromethylindole; 5-Methoxy-2-(trifluoromethyl)indole
EINECS	Contact for details

Quality Control

Our 5-Methoxy-2-Trifluoromethylindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.