Description

5-Nitro-2-(Trifluoromethyl)-1H-Indole is a high-purity, advanced pharmaceutical intermediate characterized by its unique indole core substituted with nitro and trifluoromethyl groups. This compound matters for its critical role as a versatile building block in the synthesis of complex, biologically active molecules, particularly in modern drug discovery. It is primarily needed by research institutions and pharmaceutical companies engaged in developing new therapeutic agents, agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and stability.
• Material Science: Acts as a building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its electron-withdrawing properties.
• Chemical Synthesis: Employed in organic chemistry research for constructing complex heterocyclic compounds and in cross-coupling reactions.
• Biochemical Probe Development: Utilized in creating fluorescent tags or molecular probes for studying biological processes.

Basic Information

Product Name	5-Nitro-2-(Trifluoromethyl)-1H-Indole
CAS No.	174734-30-6
Molecular Formula	C9H5F3N2O2
Molecular Weight	230.15 g/mol
Synonyms	5-Nitro-2-(trifluoromethyl)-1H-indole; 2-(Trifluoromethyl)-5-nitro-1H-indole; 1H-Indole, 5-nitro-2-(trifluoromethyl)-; 5-Nitro-2-trifluoromethylindole; 174734-30-6; 5-Nitro-2-(trifluoromethyl)indole; 2-Trifluoromethyl-5-nitroindole
EINECS	Contact for details

Quality Control

Our 5-Nitro-2-(Trifluoromethyl)-1H-Indole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP standards where applicable to support our clients in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.